45601 Ohio Commercial Properties for Sale

45601 Ohio Commercial Properties for Sale

$399,000
226032591 MLS
Turnkey commercial opportunity at 1987 Western Avenue in Chillicothe. This 1.0-acre corner property was previously operated as a car dealership and is zoned Commercial, making it well-suited for auto sales, auto service, or a similar business use. The main building offers 1,456 square feet, with a total of 43,560 square feet of available site area and parking for up to 80 vehicles -- ideal for a dealership, service center, or fleet-based operation. Located in a high-traffic area, this property combines visibility and functional space for a new owner-operator or investor looking to continue its automotive use or repurpose the site for another business venture.

1987 Western Avenue, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC
$500,000
226031861 MLS
Hooks Pizza has served Chillicothe, OH since 2009 and built a loyal, established customer base over 15+ years in business. This is a turn-key operation, ready for a new owner to step in and run day one. It's a strong fit for an investor adding a proven local business to their portfolio, or for an existing pizza brand looking to expand into the Chillicothe market. The name recognition, customer base, staff, and daily operations are already in place. Two features set this business apart from competitors. First, a to-go liquor license lets the shop sell beer and packaged spirits alongside food - an additional revenue stream most nearby pizza shops don't have. Second, a drive-thru window adds a fast, convenient order option beyond dine-in and carryout, with real untapped potential: extended hours, a streamlined express menu, third-party delivery pickup, or simply capturing more volume from the fast-casual crowd. All equipment is included in the sale, and existing systems, recipes, and processes stay in place for continuity. The current owner is willing to help with hands-on training and a smooth transition for staff, suppliers, and day-to-day operations, reducing the risk of taking over an unfamiliar business. The current owner has kept operations lean and consistent for over a decade, leaving room for a new owner to grow revenue through expanded marketing, catering, and delivery app partnerships without changing what already works.

490 W 5th Street, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC
$250,000
226031470 MLS
Elford Realty is proud to present a ±2,400 SF freestanding commercial building situated on ±0.61 acres in Chillicothe, Ohio. Zoned General Commercial, the property offers a flexible opportunity for office, service, nonprofit, retail, or owner-user use, subject to applicable zoning and approvals. Located along the E. Main Street corridor, the site provides convenient access to surrounding commercial amenities and is well-positioned to serve a variety of business users.

991 E Main Street, Chillicothe

Listing Courtesy of : J. Andrew Mills ---- Elford Realty, LLC
$975,000
226022077 MLS
Incredible income-producing opportunity! This property includes a nearly 10,000 sq. ft.commercial building with approx. 4,000 sq. ft. of storefront and 6,000 sq. ft. of warehouse space. Also included is a rented, residential house, with its front yard converted into additional parking for the commercial building. Also included is a digital billboard on-site that provides steady income through both monthly and annual advertising contracts. Multiple income streams in one unique investment! Included are 7 total parcels making up just shy of an acre outside of city limits, yet located right on busy Western Ave. with roughly 18,000 cars traveling by daily. Being Sold ''As Is''.

1222 Western Avenue, Chillicothe

Listing Courtesy of : Elizabeth Ann Gerber-Gawelek ---- ERA Martin & Associates
$425,000
226022043 MLS
Versatile mixed-use opportunity on North High Street in Chillicothe. This approximately 2,600 SF commercial building offers a flexible open layout with expansive storefront windows, three commercial entrances, and the ability to divide into multiple spaces. The commercial level has been updated with electrical, plumbing, HVAC, water heater, and interior renovations, making it well-suited for retail, office, showroom, or service-based use. A partially finished basement provides additional storage or workspace. Above the commercial space is a tenant-occupied 2-bedroom apartment of approximately 1,100 SF with a separate entrance, providing an established residential income component. The property includes a total of 16 parking spaces, along with outdoor patio space, building signage opportunities, and convenient access for customers and tenants. Located minutes from downtown Chillicothe, Yoctangee Park, Adena Health System, Bridge Street amenities, and US-23 access to Columbus, this property offers strong visibility, accessibility, and long-term potential in a highly traveled commercial corridor.

275 N High Street, Chillicothe

Listing Courtesy of : Andrew J Hursh ---- The Westwood Real Estate Co.
$200,000
226009789 MLS
Prime opportunity on Main Street in Chillicothe, OH! This versatile multi-use commercial building offers excellent visibility in a high-traffic location, making it ideal for retail, office, or mixed-use investment. Situated within a Qualified Opportunity Zone, it presents valuable potential tax advantages for investors. The property includes 20 on-site parking spaces, a rare convenience in this area. Whether you're expanding your business or building your portfolio, this property is priced to sell and ready for its next chapter.

83-85 W Main Street, Chillicothe

Listing Courtesy of : Brad N. Park ---- Dwell Real Estate, LLC

Selling Office: Dwell Real Estate, LLC.

$240,000
225011196 MLS
Versatile commercial property in a prime location just off Western Ave., only 5 minutes from downtown! This well maintained building is perfect for a doctor or dentist office, counseling center, salon/spa, insurance agency or accountants office. Handicap accessible with 16 parking spaces in a newly paved lot. Inside, you'll find 5 offices/exam rooms, 2 waiting rooms,(one with a gas fireplace), a kitchen, 1 full bath and 2 half baths. The exterior features elegant stonework, while the interior boasts luxury vinyl plank flooring and fresh paint. This property also offers the potential for a live/work setup. A fantastic opportunity in a high demand area.

10 Dun Road, Chillicothe

Listing Courtesy of : Elizabeth Ann Gerber-Gawelek ---- ERA Martin & Associates

Selling Office: Dwell Real Estate, LLC.

$279,000
225024230 MLS
Prime investment opportunity in the heart of downtown Chillicothe! 23 S Paint St offers a versatile commercial building featuring one commercial space and two residential rental units, along with seven private parking spots—an invaluable asset in the downtown area. The first-floor commercial space includes front and rear entrances, a reception area, conference room/office, and a half bath, making it ideal for a variety of business uses. The upper levels feature two spacious 1-bedroom, 1-bath apartments, each with an open floor plan, front and rear entrances, and private decks. This property's excellent location offers both high visibility and walkability, making it a strong choice for investors seeking steady rental income and long-term value.

23 S Paint Street, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC

Selling Office: EXP Realty, LLC.

$100,000
225015963 MLS
Rare opportunity on a bustling main street near downtown Chillicothe! This property boasts a spacious parking lot with 60 dedicated spots spread across 0.37 acres, ensuring ample parking for customers and employees alike. Situated in a high-traffic area, this lot offers prime visibility, making it an ideal choice for retail, office space, or investment expansion. Whether you're looking to enhance accessibility for your business or secure a valuable investment, this parking lot presents endless potential. Don't miss out on this exceptional opportunity to capitalize on convenient parking in a thriving business district!

160 W Main Street, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC

Selling Office: ERA Martin & Associates.

$159,000
225015957 MLS
This exceptional property includes a private parking lot and sits on a high-traffic street, featuring two income-generating buildings that offer outstanding visibility for virtually any business. The additional 1,700 sq. ft. structure presents endless possibilities for an owner-occupant or new tenant. Its strategic downtown location makes it ideal for retail, office space, or expanding an investment portfolio. Don't miss your chance to own a valuable piece of real estate in a thriving business district with strong income potential!

166 W Main Street, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC
$154,000
224029565 MLS
This historic downtown building, dating back to circa 1803, is full of charm and untapped potential. Located on a large lot with off-street parking, it's a rare find in the city's heart. The building's timeless character shines through, awaiting the right vision to restore it to its former glory. With the possibility of creating two distinct units—commercial, residential, or a mix—this versatile space offers endless opportunities. The expansive lot allows for creative landscaping, outdoor amenities, or expansion. Don't miss the chance to transform this diamond in the rough into a true masterpiece.

72 W 2nd Street, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC

Selling Office: EXP Realty, LLC.

$63,000
224029411 MLS
Commercial garage with 6 doors.

3971 Liberty Hill Road, Chillicothe

Listing Courtesy of : NON MEMBER ---- NON MEMBER OFFICE

Selling Office: Coldwell Banker Realty.

$375,000
224022899 MLS
Located in the heart of downtown Chillicothe, this nearly 3,500 sq. ft. commercial building offers a prime opportunity for businesses. The one-level layout features multiple office spaces, including private offices, open areas, and a spacious reception area designed to make a professional first impression. Recently updated with a brand-new roof and available for immediate occupancy, the building ensures a seamless transition for your business. Private off-street parking adds convenience for employees and clients—a rare find in the bustling downtown area. With high visibility, heavy foot traffic, and a well-maintained interior, this property is ideal for businesses looking to thrive in a downtown location.

36 N Walnut Street, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC

Selling Office: Dwell Real Estate, LLC.

$79,900
224016137 MLS
Looking for a small business space? This property is located on a busy street in Chillicothe. A small office with a restroom and an additional garage with possibility of 3 bays. Large gravel parking lot, previously used as a car lot. Drive by and take a look, it has many options.

590 N High Street, Chillicothe

Listing Courtesy of : Cindy L Stevens ---- RE/MAX Revealty

Selling Office: RE/MAX Revealty.

$287,500
223033621 MLS
Great commercial location on E. Main St. Frontage on two streets. Large paved parking area.

1008 E Main Street, Chillicothe

Listing Courtesy of : Mike Miller ---- C/B REALTY CHAMPION INC

Selling Office: Coldwell Banker Realty.

$325,000
223020010 MLS
Investment opportunity for a new business. This is a street level retail property. Perfect for many uses in this open concept all-brick dwelling. Previously a gun shop. Currently used as a gym. Plenty of parking space. Close to US-23

375 Marietta Road, Chillicothe

Listing Courtesy of : Jay Reed ---- Nobility Realty, LLC

Selling Office: NON MEMBER OFFICE.

$315,000
223040390 MLS
Commercial property with great visibility from US 35 and easy access just off Main Street. Situated on one acre featuring a 40x60 building complete with two 14-foot bay doors, as well as an office space, break room, and utility room. Built in 2007, this building has been well maintained with much potential offering endless opportunity!

233 Renick Avenue, Chillicothe

Listing Courtesy of : Meredith W Tomlinson ---- EXP Realty, LLC

Selling Office: EXP Realty, LLC.

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45601 Ohio Commercial Properties

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